Located in the south of the Central Asian orogenic belt, the southern Beishan belt in Gansu Province is a key area for studying the tectonic evolution of the Central Asian orogenic belt. Its late Paleozoic tectonic setting has been controversial for a long time. In order to further explore the late Paleozoic tectonic evolution of the southern Beishan belt, the geochronology and geochemical characteristics of the Changshan monzogranite body were analyzed. The analysis results show that the LA-ICP-MS zircon U-Ph weighted average age of the Changshan monzogranite is (291.1 ± 1.5) Ma, and the emplacement of the plutons occurred in the early Permian. Geochemical datas show that the plutons are high potassium calc-alkaline and peraluminous series rocks. The results show that SiO₂ ranges from 72.07% to 72.94%, K_2O ranges from 4.93% to 5.10%, and the contents of K₂O > Na₂O, A1₂O₃ ranges from 13.52% to 13.97%. The curves of chondrite-normalized REE are obviously right inclined, and the LREE are relatively enriched (LREE/HREE are 10.96 ~ 14.98), δEu are 0.78 ~ 0.92, with weak negative Eu anomaly. Trace elements are relatively enriched in LILE(large ion lithophile elements), depleted HFSE (high field strength elements), and significantly depleted in high field strength Elements Nb, Sm, Y. According to the regional tectonic setting, petrological and geochemical characteristics, the Changshan adamellite plutons are considered to be the product by post-collisional magmatic activity, reflecting the completion of the collision collage on the southern margin of the Central Asian orogenic belt in the early Permian.