The applicability of prefabricated subway station structures in inclined liquefiable sites was investigated. Based on the actual project of Shuangfeng subway station in Changchun City, the finite difference software FLAC3D was used to carry out the seismic response analysis of prefabricated subway station structures in liquefiable soil, for example, the pore water pressure of the foundation, the lateral motion of the liquefied soil, the dynamic response and uplift characteristics of the subway station structure, and the deformation characteristics of the prefabricated subway station structures were analyzed. The results show that the negative pore pressure phenomenon of pore water pressure on both sides of prefabricated subway station under inclined liquefiable site conditions is present, and the phenomenon becomes more obvious the closer the location of the station structure is to the station, and at the same time, the negative pore pressure of the soil on the left side of the structure (uphill) is significantly greater than that on the right side (downhill). The further away the foundation soil is from the station structure, the more pronounced the liquefaction is. The phenomenon of lateral slippage of the surrounding soil is significantly suppressed by prefabricated subway station structures. The principal stresses in the upslope sidewall (member C1) are greater than those in the downslope sidewall (member C2), and the principal stresses at the bottom of the upslope sidewall of the structure are greatest, so the upslope sidewall of the structure should be given priority in the seismic design.