A large amount of dredged silt is produced in Taihu Lake every year. In order to realize the resource utilization of solid waste, the feasibility of preparing dredged mud and attapulgite into vertical cutoff wall material was explored, and its impermeability was studied. The permeability resistance and micro-pore structure of dredged mud-attapulgite engineering cutoff wall materials were studied by flexible wall infiltration, water centrifugation and low field nuclear magnetic resonance test. The results show that with the increase of consolidation pressure, the proportion of small holes increases, the proportion of mesoporous holes decreases, the content of free water decreases, and the content of bound water is basically unchanged, and the porosity and hydraulic conductivity of dredged silt-attapulgite decrease gradually with the increase of consolidation pressure. At the consolidation pressure of 100 kPa, the porosity and hydraulic conductivity of the dredging silt-attapulgite cutoff wall material using zinc chloride and butyric acid as the contaminated permeate increase compared with the test using water as the permeate. The reason is that the addition of the polluted permeate reduces the small hole proportion, increases the mesoporous proportion, increases the free water content, and basically keeps the bound water content unchanged.