An adaptive predefined-time prescribed performance backstepping fault-tolerant control strategy is presented based on radial basis function (RBF) neural networks, event-trigger mechanism and hysteresis quantizer for the attitude control problem of quadrotor unmanned aerial vehicle (UAV) with actuator faults. Firstly, the dynamic model of the quadrotor UAV system was constructed, and the attitude model was reconstructed by incorporating the actuator fault model. Secondly, by designing a class of time-varying functions, the error variables required for backstepping control were transformed. Thirdly, the nonlinear function approximation capability of RBF neural networks was utilized to estimate derivatives of virtual control laws and the actuator fault with unknown parameters. Finally, to reduce the update frequency of the actuator, a combination of event-trigger mechanism and hysteresis quantizer was used to design the control input. Stability of the closed-loop system was demonstrated through Lyapunov stability theory. The effectiveness of the proposed algorithm was verified through MATLAB. It is concluded that the designed event-triggered quantized controllers have a lower update frequency compared to controllers designed using only event-triggered techniques.