In order to explore the problem of fracturing fluid filtration in the process of open hole fracturing, based on the classical filtration model, combined with the two-dimensional model of hydraulic fracturing, ABAQUS finite element software was used for simulation calculation. It is found that in the initial stage of fracture propagation, the pore pressure increases rapidly and increased linearly, and the filtration loss of fracturing fluid also increase rapidly, which is the initial stage of fracture propagation. With the continuous injection of fracturing fluid, the increasing trend of pore pressure becomes slower, and the filtration loss of fracturing fluid also increases slowly. As the crack width gradually widens, it is the crack propagation stage. In the later stage of fracture propagation, when the fracture length reaches a certain length, the change of pore pressure is gradually stable, and the filtration loss of fracturing fluid is slightly reduced compared with the pressure holding state and the fracture propagation stage. In the whole process, the calculation of filtration loss takes into account the dynamic expansion of cracks, which is of certain significance for the actual engineering filtration situation.