In order to study the effect of low temperature on mechanical properties, fatigue properties and frost resistance of cement stabilized crushed stone mixture in cold area. Using 5 ℃, 10 ℃, 15 ℃ to simulate the field low temperature curing condition, based on the mechanical properties test, three-point loading fatigue test and freeze-thaw cycle test, the differences of unconfined compressive strength, flexural tensile strength, dynamic resilience modulus, fatigue resistance and anti-freezing durability of cement stabilized gravel mixture under low temperature curing condition, 20 ℃ standard curing condition and 30 ℃ curing condition were compared. The effect of curing temperature on the attenuation law of microvoid structure of cement-stabilized crushed stone mixture during freeze-thaw cycle test was studied. The results show that, compared with the standard curing temperature (20 ℃), the mechanical properties of cement stabilized macadam mixture decrease by 20% ~ 40% and the fatigue life decrease by 40% ~ 50% under the condition of 5 ~ 10℃. Low temperature curing has a significant deterioration effect on the mechanical properties, fatigue properties and anti-freezing properties of cement stabilized macadam mixture. The greater the decrease of mechanical properties and fatigue characteristics of cement stabilized crushed stone mixture. Increasing the curing temperature is helpful to reduce the decay rate of micro void diameter after freeze-thaw cycle, increase the stability of the void structure of cement stabilized gravel mixture and refine the micro void structure during the freeze-thaw cycle test, and thus increase the mechanical properties, fatigue durability and frost resistance of cement stabilized gravel mixture.