The Chang 6₃ sand formation in Block A of Ordos Basin is an ultra-low permeability reservoir, which is difficult to be conventionally exploited. At present, horizontal well fracturing is widely used for development. According to the physical characteristics of ultra-low permeability reservoir, the geomechanical model and fracturing simulation software, combined with embedded discrete fracture method were used to characterize the artificial fractures generated by fracturing simulation of Chang 6₃ sand formation, and carried out numerical simulation research based on this. Through this integrated process, the integrated simulation of complex fracturing of horizontal wells were realized, and the efficiency of horizontal well development was improved. The results show that the embedded discrete fracture method can effectively combine fracturing and numerical simulation, and realize the integrated flow from fracturing to numerical simulation of horizontal wells. The accuracy of the numerical model was verified by the historical fitting of the production mode of fixed oil production. By adjusting the relevant parameters to optimize the model, it is more in line with the actual production situation of the well group, which is conducive to the subsequent development plan adjustment and production forecast.