Based on the detailed process mineralogy of gold ore from Jierwushake gold deposit in west Junggar, the selectability test was carried out. The results show that the valuable element in the ore is Au with a grade of 3.61 g/t. The types of gold minerals are natural gold, silver-gold, gold-tellurium and gold-selenium-silver ore, and the embedded states are encapsulated gold, fracture gold and intergranular gold. The particle size is mainly microparticle gold (0.2 ~ 10.0 μm), accounting for 96.96%, and the number of fine and above gold particles (> 10 μm) account for 3.04%. The flotation-leaching combined process is recommended for mineral processing test: the Au grade of flotation-flotation concentrate is 53.14 g/t, and the recovery rate is 31.69%. After leaching the whole sludge of flotation tailings for 24 hours, the gold content in tailings is 0.20 g/t, and the leaching rate of gold operation is 89.56%, the Au total recovery rate of combined process is 93.31%, and the instructions are ideal.