In order to enhance the safety and efficiency of operations in the double-channel U-shaped apron area of large airports, an optimized operational procedure for the double-channel U-shaped area was studied. Firstly, the utilization and partitioning of taxiways in the double-channel U-shaped apron area were designed, and the positions of pushback holding points were optimized. Secondly, based on the partitioning of the double-channel U-shaped apron area and the optimized positions of pushback holding points, different operational procedures for aircraft were designed for various scenarios. Then, evaluation indicators were designed from the perspectives of safety and efficiency, and corresponding evaluation models were established. Finally, simulation experiments were conducted using Wuhan Tianhe Airport as the object. The results show that the proposed optimized operational procedure can reduce the total operation time by 13.3%, total waiting time by 31.4%, and waiting rate by 22.4%. The flight density was gradually increased until reaching the maximum theoretical capacity of the U-shaped apron area, and further verification was conducted. The results indicate that the proposed optimized operational procedure performs better across different indicators under varying flight volumes, verifying its effectiveness and providing theoretical references for current and future operational procedures of double-channel U-shaped apron areas.