Unique test requirements in civil large aircraft flight testing, characterized by short task durations, wide measurement point distribution, and numerous measurement locations, are addressed. Challenges in the existing wired Ethernet-based onboard data acquisition systems, including difficult measurement equipment installation, complex test cable layout, and prolonged retrofitting periods, are identified. A flexible, miniaturized, and compact space-compatible measurement system for critical wing structural state parameter measurements during civil aircraft flight testing was proposed. An integrated microsystem, including a flexible antenna module and a multi-sensor parameter collection module, was developed and integrated into the civil aircraft wing. The system's reliability and stable signal transmission were demonstrated. The design and application of a wireless flexible measurement system for wing state monitoring on civil aircraft were detailed. The system design approach, data transmission strategy, and integration with third-party loggers were described. Ground and flight tests were conducted to collect data. The onboard flexible system's capability to measure temperature, three-axis vibration, and pressure is verified.