In order to reasonably evaluate, screen, and optimize the exterior design schemes of suspended monorail train with regional cultural characteristics, an optimization method for exterior design of suspended monorail train based on fuzzy analytic hierarchy process was proposed. Firstly, the characteristics and trends of the exterior design of suspended monorail trains both domestically and internationally were analyzed, and an evaluation index system which focusing on cultural factors for the exterior design of suspended monorail train was constructed. Then, estimate matrix based on experts scores and gained weights of each individual index by calculation was established. Finally, taking the design case of a suspended monorail train with regional cultural characteristics of Guangzhou as an example, the integration of typical regional culture and design idea, as well as the evaluation and optimization of design schemes were explained. The results show that the method can be used to screen and obtain suspension monorail train design schemes with high comprehensive satisfaction in terms of exterior form, painting, and cultural relevance. It can quantitatively evaluate design schemes from multiple dimensions and provide a basis and direction for the screening and iterative optimization of design schemes.