Because of its high working density and narrow space, apron becomes the collision accident prone area. The current collision risk assessment model does not consider human factors. To solve this problem, a dynamic assessment method of apron collision risk incorporating different human factors was proposed to quantitatively calculate the collision risk of apron operation. Based on this method, the simulation experiments were carried out in combination with the actual operation of the airport. The experimental results show that human factor is an important factor that cannot be ignored in the calculation of apron collision risk. The impact of work load on collision risk is greater than that of work experience. Taxiing aircraft can pose a greater threat to apron safety than launching aircraft. It is suggested that when the personnel work load is large, the appropriate extension of the safety distance is conducive to ensuring the safety of the apron operation.