To study the effect of high voltage pulsed electric field on hair dyeing effect, black hair from the people of 18 ~ 28 years old and hair dyes were used as test materials. The dyeing experiment was conducted by treating hair and hair dyes with high-voltage pulsed electric fields and the red green blue (RGB) model values of the hair after dyeing were extracted as response values. With the help of equal response surface methodology, the mathematical model on the effect of high voltage pulsed electric field parameters including electric field intensity, pulse width, and pulse number were conducted and analyzed. The results show that applying high voltage pulsed electric field simultaneously to both hair and hair color can raise the blue channel value B of RGB parameters by 3.7% and the related optimized parameters of electric field intensity, pulse width and pulse number are 1 125 V/mm, 175 μs and 52. Therefore, treating hair and hair dye with high-voltage pulse electric field before dyeing would enhance the coloring effect and lay a specific foundation for the optimization of hair dyeing process.