为了阐明油气开采中蜡和水合物的相互作用机理，通过分子动力学模拟方法研究了蜡晶体对水合物成核、生长、聚集和晶体结构的影响。结果表明，蜡晶体对水合物的形成有促进与抑制双重作用。在低至中浓度的含蜡体系中蜡晶体会吸引周围的甲烷分子向蜡晶体运移，从而使蜡晶体附近的水溶液中甲烷溶解浓度增加，水合物形成驱动力提高。然而高浓度的蜡分子由于具有较强的吸附特性因此会使甲烷分子在其表面形成气膜，在这种情况下，由于水相中甲烷浓度的降低会使水合物的形成受到抑制。这项研究的成果将会为后续油气输送管道中蜡与水合物的堵塞预防打下基础。

In order to elucidate the interaction mechanism between wax and hydrates in oil and gas extraction, molecule dynamics simulations was used to investigate the effects of wax crystals on hydrate nucleation, growth, aggregation, and crystal structure. The results show that wax crystals exhibit a dual role in both promoting and inhibiting hydrate formation. In low-to-medium concentration wax-containing systems, wax crystals attract surrounding methane molecules to their vicinity, thereby increasing methane concentration in the adjacent aqueous phase, which strengthens the driving force of hydrate formation. However, in high-concentration wax systems, the strong adsorption properties of wax molecules lead to the formation of a gas film of methane molecules on their surfaces. In this scenario, the reduced methane concentration in the aqueous phase suppresses hydrate formation. The findings of this study will lay a theoretical foundation for preventing wax-hydrate blockages in oil and gas pipelines.