CO₂驱油技术作为成熟的三次采油技术，已经广泛在非均质性强的复杂小断块油田中应用。然而CO₂驱油气窜严重，导致驱油效率改善普遍低于10%。为此，通过泡沫调剖封堵，寻求提高CO₂驱油效率的方法。以JS油田为例，对比了气溶性封窜剂G-CF4与W-CF1水溶性封窜剂的泡沫性能，并测试了泡沫性能更佳的封窜剂的封堵性能及提采效果。结果表明，在目标储层条件下，最佳泡沫体系为0.25%的G-CF4。同时，岩心组合渗透率级差越大，G-CF4在高渗透率岩心中的封窜能力越强，88 mD级差中高渗透率岩心的阻力系数是50 mD级的2.5倍。在88 mD级差岩心组合中，G-CF4可将高渗透率岩心的阻力系数维持在9.2以上。先注入0.25%的G-CF4溶液0.3 PV，再通过CO₂驱油，可提高原CO₂驱油效率15%。研究结果为JS油田泡沫封堵技术的优化提供室内实验支持。

CO₂ flooding technology, recognized as a mature tertiary recovery method, is widely applied in complex small fault-block oilfields with strong heterogeneity. However, severe gas channeling is commonly observed during CO₂ flooding. As a result, the improvement in oil displacement efficiency remains low, typically below 10%. To address this, effective methods were explored to enhance oil displacement efficiency. Foam profile control and plugging were utilized as key techniques to achieve this enhancement. In the experiment, the JS oilfield was used as an example. The foam performance of the gas-soluble foaming plugging agent G-CF4 and the water-soluble foaming plugging agent W-CF1 was compared. The plugging agent with better foam performance was selected. Its plugging ability and oil displacement efficiency were tested. The results show that under target reservoir conditions, the optimal foaming plugging agent is 0.25% G-CF4. Moreover, the greater the permeability difference within the core combination, the stronger the plugging effect of G-CF4 in high-permeability cores. For a core combination with a permeability difference of 88 mD, the resistance coefficient of high-permeability cores is 2.5 times higher than that of a core combination with a permeability difference of 50 mD. In the core combination with 88 mD permeability difference, G-CF4 can maintain the resistance coefficient of high permeability cores above 9.2. The injection of 0.25% G-CF4 solution for 0.3 PV, followed by CO₂ flooding, improves oil displacement efficiency by 15% compared to CO₂ flooding alone. This study provides laboratory evidence supporting the optimization of foaming plugging technology in the JS oilfield.