随着中国空间站投入使用，物资保障已成为重中之重，目前物资主要是通过货运飞船货包形式上行，采用货物外层包裹泡沫缓冲材料，整体捆绑固定于货架蜂窝夹层板的承载方式，在上升段有较大的力学响应，如何降低产品无用的抗力学重量，提高货运飞船有效载重比是这篇文章的研究内容。通过研究F4型货包，建立了以结构柔顺性为目标函数的拓扑优化模型，分别对3个设备的4种减重工况进行了仿真分析和试验，结果证明利用该模型可有效减轻设备重量。

With the operation of the Chinese space station, material support has become a top priority. At present, materials are mainly transported in the of cargo packages through freight spacecraft, using foam cushioning materials on the outside of the cargo, and overall binding and fixing on the honeycomb sandwich panel of the. There is a large mechanical response during the ascent stage. How to reduce the useless mechanical weight of the product and increase the effective payload ratio of the freight spacecraft the research content of this article. By studying the F4 type cargo package, a topology optimization model with structural compliance as the objective function was established, and simulation and experiments were conducted on four weight reduction conditions of three devices. The results prove that the model can effectively reduce the weight of the equipment.