文物保护单位是中华优秀传统文化的重要载体。研究文保单位空间分异及多尺度驱动因子结果差异，对持续推进历史文化传承、繁荣发展地区文化事业和文化产业具有重要意义。以徽州地区文物保护单位为研究对象，运用标准差椭圆、核密度估计以及地理探测器等方法，对文保单位时空分异及驱动因子进行全面分析。结果表明：徽州地区文保单位呈现“分散-集中-分散”的时间序列特征，且分布中心逐步由中部向南偏移；文保单位空间聚集特征显著，整体表现为“V”字形分布格局，具体集中在歙县和绩溪县；自然地理因子与人文地理因子皆对文保单位空间分异产生影响。

Cultural relics protection units are important carriers of Chinese outstanding traditional culture. It is of great significance to study the spatial differentiation of cultural relics protection units and the differences in the results of multi-scale driving factors, in order to continuously promote the inheritance of history and culture, and to prosper the development of regional cultural undertakings and cultural industries. Huizhou cultural relics protection units were taken as the research object, and standard deviation ellipse, kernel density estimation and geographic detector methods were used in the analysis of spatial and temporal differentiation and driving factors of cultural relics protection units. The results show that the cultural heritage units in Huizhou region present the time series characteristics of "dispersed-concentrated-dispersed", and the center of distribution gradually shifts from the middle to the south. The spatial aggregation of cultural heritage units is remarkable, the overall performance of the "V" distribution pattern, specifically concentrated in Shexian County and Jixi County. Natural geographic factors and human geographic factors have an impact on the spatial differentiation of cultural heritage units.