抗生素为水环境中新型污染物，对水生生态环境以及人类的健康有潜在的威胁。针对磺胺类抗生素难降解氧化且并不能完全被污水处理厂高效去除，构建Fe₇₈Si₉B₁₃/H₂O₂体系高效环保降解磺胺类抗生素污染。通过一系列不同的实验参数实验遴选出，Fe₇₈Si₉B₁₃/H₂O₂体系作为高效降解磺胺嘧啶（sulfadiazine, SDZ）的最佳工艺。实验结果表明，在pH＝2，H₂O₂＝50 μmol/L，温度为25 ℃时，能使250 μg/L SDZ在4 min内100%降解，其表观速率常数（K_obs）可达0.99 min^-1，其体系中去除SDZ的活化能为25.42 kJ/mol。淬灭剂实验证明Fe₇₈Si₉B₁₃/H₂O₂体系降解SDZ的关键活性物质是羟基自由基（·OH）。通过高分辨鉴定中间体以及对中间体进行毒性评估，结果表明所有中间体相比母本都大幅度减少或无害。此外，通过实际水体降解实验，验证了该氧化降解体系实际应用潜力。

Antibiotics are new pollutants in water environment, which have potential threat to aquatic ecological environment and human health. Considering that sulfanilamide antibiotics are difficult to degrade and oxidize and cannot be effectively removed by sewage treatment plants, Fe₇₈ Si₉ B₁₃/H₂ O₂ system was constructed to efficiently and environmentally degrade sulfanilamide antibiotic pollution. Fe₇₈ Si₉B₁₃/H₂O₂ system was selected as the best process for efficient degradation of SDZ(sulfadiazine) through a series of experiments with different experimental parameters. The experimental results show that 250 μg/L SDZ can be degraded 100% within 4 min at pH = 2, H₂O₂=50 μmol/L and temperature 25 ℃, and its apparent rate constant (K_obs) can reach 0.99 min^-1. The activation energy of SDZ removal in the system is 25.42 kJ/mol. The quenching agent experiments show that the key active substance of Fe₇₈Si₉B₁₃/H₂O₂ system degrades SDZ is hydroxyl radical (·OH). Through high resolution identification of intermediates and toxicity assessment of the intermediates, the results show that all intermediates are substantially reduced or harmless compared to the mother. In addition, the practical application potential of the oxidation degradation system is verified through the actual water degradation experiment.