光生物调节疗法对慢性阻塞性肺疾病肌肉功能障碍的研究机制进展

赵东凯 ,  费鑫如 ,  杨桂仙 ,  刘俊楠 ,  刘通

科学技术与工程 ›› 2025, Vol. 25 ›› Issue (2) :439-447

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科学技术与工程 ›› 2025, Vol. 25 ›› Issue (2) :439-447 DOI: 10.12404/j.issn.1671-1815.2401160
医药、卫生

光生物调节疗法对慢性阻塞性肺疾病肌肉功能障碍的研究机制进展

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Advances in the Research Mechanism of Photobiomodulation Therapy on Muscle Dysfunction in Chronic Obstructive Pulmonary Disease

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摘要

肌肉功能障碍作为慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)的常见肺外表现之一,限制了COPD患者的运动能力、心肺健康和生活质量,导致预后不良。光生物调节疗法(photobiomodulation therapy, PBMT)作为一种新兴的COPD肌肉功能障碍辅助治疗技术在临床中被广泛推广使用,在减轻肌肉炎症、缓解肌肉疲劳、改善肌肉代谢、增加肌肉耐力、加速肌肉愈合等方面发挥积极作用。对中外PBMT作用于COPD肌肉功能障碍的康复机制及其应用现状进行了综述,旨在为PBMT应用于COPD肌肉功能障碍的康复治疗提供参考。

Abstract

Muscle dysfunction, as one of the common extrapulmonary manifestations of COPD (chronic obstructive pulmonary disease), limits the exercise capacity, cardiorespiratory health, and quality of life of COPD patients, leading to poor prognosis. PBMT(photobiomodulation therapy) an emerging adjunctive treatment for COPD-related muscle dysfunction, has been widely promoted and utilized in clinical practice. It positively affects muscle inflammation, alleviates muscle fatigue, improves muscle metabolism, enhances muscle endurance, and accelerates muscle healing. The comprehensive review of the rehabilitation mechanisms and current application status of PBMT (photobiomodulation therapy) in addressing COPD (chronic obstructive pulmonary disease)-related muscle dysfunction, both domestically and internationally, is conducted to offer insights and guidance for the application of PBMT in the rehabilitation treatment of COPD-related muscle dysfunction.

关键词

慢性阻塞性肺疾病 / 光生物调节疗法 / 骨骼肌 / 呼吸肌

Key words

COPD(chronic obstructive pulmonary disease) / photobiomodulation therapy / skeletal muscle / respiratory muscle

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赵东凯, 费鑫如, 杨桂仙, 刘俊楠, 刘通. 光生物调节疗法对慢性阻塞性肺疾病肌肉功能障碍的研究机制进展[J]. 科学技术与工程, 2025, 25(2): 439-447 DOI:10.12404/j.issn.1671-1815.2401160
ZHAO Dong-kai, FEI Xin-ru, YANG Gui-xian, LIU Jun-nan, LIU Tong. Advances in the Research Mechanism of Photobiomodulation Therapy on Muscle Dysfunction in Chronic Obstructive Pulmonary Disease[J]. Science Technology and Engineering, 2025, 25(2): 439-447 DOI:10.12404/j.issn.1671-1815.2401160

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基金资助

吉林省教育厅科学技术研究项目(JJKH20241043KJ)

吉林省科技发展计划(20200404066YY)

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