
科学技术与工程

中国技术经济学会
心脏磁共振成像技术研究阻塞性睡眠呼吸暂停低通气综合征患者左心功能及心肌的变化分析
侯博 , 李文龙 , 申兵 , 张世斌 , 申玉霞
科学技术与工程 ›› 2025, Vol. 25 ›› Issue (4) :1378-1382
心脏磁共振成像技术研究阻塞性睡眠呼吸暂停低通气综合征患者左心功能及心肌的变化分析
Left Ventricular Function and Myocardial Changes in Patients with Obstructive Sleep Apnea-hypopnea Syndrome Using Cardiac Magnetic Resonance Imaging
探析心脏磁共振成像技术(cardiac magnetic resonance imaging, CMRI)应用于评估阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome, OSAHS)患者左心功能及心肌的变化效果。选择邯郸市中心医院2019年11月—2021年6月就诊的31例OSAHS患者作为观察组,选择同期接受CMRI监测的30例健康志愿者作为对照组。对比两组左心功能相关参数,包括:左心室射血分数(LVEF)、左心室舒张末期/收缩末期容积(LVEDV/LVESV)、左室心肌活性成像指标[左心室心肌平均注射对比剂前T1pre值(在增强前T1弛豫时间的测量值)、注射后15 min T1post值(在CMRI中,使用对比剂后的T1 mapping技术所测量的心肌组织的T1值)、T2值(心肌组织的横向弛豫时间)]、不同心肌层面组织学参数特征[左室心肌平均细胞外间质容积分数(ECV)]。观察组左心功能参数(LVEF左心室射血分数LVED左心室舒张未期内径)均明显低于对照组,而LVESV、T2值明显高于对照组(P < 0.05)。观察组T1pre、T1post值、基底段、中间段、心尖段ECV与对照组无统计学差异(P > 0.05)。CMRI应用于OSAHS患者中临床效果显著,可有效评估患者的左心功能、结构及心肌早期病变。
To explore the effects of cardiac magnetic resonance imaging(CMRI) on the assessment of left ventricular function and myocardial changes in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Thirty-one patients with OSAHS who were admitted to Handan Central Hospital from November 2019 to June 2021 were selected as the observation group, and 30 healthy volunteers who received CMRI monitoring during the same period were selected as the control group. Two sets of parameters related to left ventricular function were compared, including left ventricular ejection fraction (LVEF), left ventricular end diastolic/end systolic volume (LVEDV/LVESV), left ventricular myocardial activity imaging indexes[T1pre value(measurement of T1 relaxation time before enhancement) before mean injection of contrast agent in left ventricular myocardium, 15 min T1post value(T1 value of myocardial tissue measured by T1 mapping technique after using contrast agent in CMRI) and T2 value(transverse relaxation time of myocardial tissue)] after injection, and histological parameter characteristics of different myocardial layers [mean extracellular matrix volume fraction (ECV) of left ventricular myocardium]. The left ventricular function parameters (LVEF, LVED) in the observation group are significantly lower than those in the control group, while LVESV and T2 values are significantly higher than those in the control group(P < 0.05). There is no significant difference in T1pre, T1post, ECV in basal segment, middle segment and apical segment between the observation group and the control group (P > 0.05). CMRI has a significant clinical effect in patients with OSAHS and can effectively assess the left ventricular function, structure and early myocardial lesions.
心脏磁共振成像(CMRI) / 左心功能 / 心肌病变 / 阻塞性睡眠呼吸暂停低通气综合征(OSAHS)
cardiac magnetic resonance imaging(CMRI) / left heart function / myocardial lesions / obstructive sleep apnea hypopnea syndrome(OSAHS)
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