Under the overarching vision of Healthy China, the imperative to investigate the design of health-oriented streets has gained paramount importance, aligning with the humanistic and sustainable evolution of urban landscapes. Addressing the limitations of existing health street evaluation methodologies marked by intricate indices, misalignment with the current state of China's streetscapes, and a dearth of quantitative scrutiny, exploratory factor analysis was employed to distill latent variables. Through a structured approach encompassing health questionnaire analysis, structural equation modeling, and the quantification of health determinants, the research localizes health parameters and constructs a robust, quantifiable evaluation framework for street health. The analysis uncovers that four latent variables demonstrating significant positive correlations with street health outcomes, listed in descending order of influence magnitude: (1) street quality improvement, (2) accessible transportation provision, (3) vibrant block development, and (4) healthy environment promotion. The structural equation model-based quantitative analysis of street health elements furnishes scientific and empirical underpinnings for the development of superior health-conscious urban blocks. This methodological advancement not only refines the precision of street design geared towards health but also elevates the living standards of residents, thereby contributing to the realization of Healthy China's aspirations.