: The research on hydrodynamic configuration of amphibious vehicle is gradually shifting from low and medium speed configuration to high speed configuration. In order to solve the problems of high speed resistance and strong wave generation of amphibious vehicle, the configuration of M-Hull ultra-high speed amphibious vehicle is proposed in this paper, and the numerical analysis of different direct navigation conditions of the vehicle is carried out based on computational fluid dynamics method. The analysis results show that this configuration can improve the overall hydrodynamic lift of the vehicle body by absorbing the first wave, significantly reduce the resistance of the amphibious vehicle on water, and achieve good longitudinal stability through reasonable design of the center of gravity position.