Lunar exploration is a strategic project of our country, the last and most crucial step is the construction of lunar research stations. In order to provide some experience for the construction of the lunar research station, a rigid and flexible coupled inflatable deployable lunar research station configuration design is proposed in this paper, and the design uses and functions of each layer are introduced. Commercial software ABAQUS was used to simulate and analyze the static load condition of the designed station on the lunar surface without the influence of the lunar earthquake and the dynamic load condition under the influence of the lunar earthquake. The results show that the structure of each layer of the station presented in this paper can maintain good mechanical properties under both conditions. It can be seen that the designed research station has good implementability and can provide some help for engineering practice.