In order to study the influence of wind on the roof of mountain sports technical building under extreme environment, taking the technical building of Beijing 2022 Winter Olympic Winter Games Center as the research background, based on CFD fluid dynamics software, SST Turbulence model was used for numerical simulation analysis. Firstly, the influence of grandstand on the wind pressure on the upper and lower surfaces of the roof is analyzed. It is found that the setting of the bleachers will weaken the positive pressure on the lower surface of the roof and increase the negative pressure on the upper surface. Then, the wind load on the upper and lower surfaces of the roof of the technical building with stands under different mountain surrounding conditions is analyzed. It is found that the negative pressure on the upper surface edge of the roof is significantly greater due to the flow separation phenomenon. From the analysis of aerodynamic interference, it can be seen that the wind pressure on the upper surface of the roof is significantly reduced by the three side ring mountains, and the wind load on the upper surface of the roof will be increased by the two sides of the mountain ring. Finally, according to the research results, some suggestions are put forward, which provide a theoretical reference for wind resistant design and site selection of buildings in mountainous areas.