In the system of flotation by external potential-control, due to the difference of corrosion potential between external potential-control electrode and sulfide minerals, when electrode collides with sul-fide minerals, it can generate galvanic corrosion. In the process of flotation by external potential-control, based on the corrosion electrochemistry, the influence of galvanic corrosion induced by electrode and sulfide minerals on the flotation of sulfide minerals has been investigated. Influence of galvanic corrosion on the flotation of sulfide minerals was relevant to electrode polarity, electrode material and flotation character of mineral. In the process of flotation, when the oxidation of mineral surface is needed, working electrode should be anode and the electrode material should have high corrosion potential; when the reduction of mineral surface is needed, working electrode should be cathode and the corrosion potential of electrode material should be lower than that of minerals. In order to eliminate the influence of galvanic corrosion induced by electrode and minerals on flotation, the corrosion potential of external potential-control electrode must be equal or close to the corrosion potential of aimed mineral. The results of this research show great importance on the selection of electrode material, selection of electrode polarity and successful flotation in the process of flotation by external potential-control.