TThe design of a eight DOF vibration damping base mechanism, and use Creo2.0 with complete assembly process of the base; the structure of the base in the application of the damping spring rod a handicapping combined with tooth tooth fracture energy absorption principle. According to Darren Bell principle, the model is simplified in the condition of conventional large equipment transportation, and the kinematic equation is established, and the appropriate vibration model evaluation mechanism is established. By using MATLAB and other software, the time domain model established by filtering and white noise is solved. The accurate simulation analysis is provided for the vertical amplitude, the elevation angle and the inclination angle of the upper end of the base. Finally, through theoretical model building and simulation analysis, the reliability of the base is verified in a certain speed range, which provides theoretical support for the subsequent application in practical production and lays a foundation.