Yangla Copper Deposit is a large copper mine，this work belongs to the old mine deep and periphery replacement resources prospecting project.Analysis the physical properties of Mine Rock (Ore) Body, carried out EH4, IP sounding , high-precision magnetic survey and Borehole IP in the riverside ore section, analysis the anomalous characteristics of different geophysical methods, the results of different geophysical methods are verified and complemented each other. Studying the comprehensive geophysical anomalies, inferred that the granite rock mass forms a nearly north-south ridge in the deep, arranged drilling ZKJ2-1 to verification the geophysical anomalies. ZKJ2-1 reveals one layer of skarn copper orebody and one layer of low-grade copper orebody at the presumed location of skarn belt. Analysis the ZKJ2-1 and Borehole IP results, it is proposed that the next prospecting direction is the rock mass depression zone east of ZKJ2-1, which could explore skarn copper orebody, and the west of ZKJ2-1, which could prospect lead-zinc deposit.Comprehensive geophysical prospecting has achieved good prospecting results in riverside ore section, and the method combination can be popularized and applied in similar deposits.